I can't really comment on a ratio between end tank and core, more as a lot of the cheaper chinese alloy radiators just don't fit from oversized end tanks etc.
I had a bit of a look around for you, and i came across a company called Fenix, which are originally from NZ, i have heard of them before, but i can't say from experience whether they are good or not. I had a bit of a look online, and i haven't found a bad thing about them, so it's up to you to do your research if you want to use them.
http://www.fenixradiators.com.au/radiator-toyota-mr2-fenix-radiators-1 Unfortunantley we get shafted compared to the other two models of r2, particularly in off the shelf options for a lot of parts, mishimoto for instance make radiators and elec fan/shroud kits for the other two models.
As for room with another water to air head exchanger, as long as you dont retain a/c, its really easy, if you do there is a bit more work involved. I run the large frozen boost core with a standard radiator behind it, and standard fans on the back.