Honestly, i'd love to do it, but the extra cost of the ferry, extra time away from work, extra time for accommodation combined with the very real possibility of break down and repair or truck home has killed this one for me.
I'd consider a drive to SA or a real road trek to WA (QLD or VIC no drama) but just can't really commit to map o' TAS. I hate to be a naysayer but for me, after a lot of thought and consideration i say 'nay'.
Sorry. (I can say I have been to Hobart and would like to return, Cascade on tap there is very nice... but its a 'fly in fly out' proposition)