I doubt you guys are going to have much success improving turbo spool if you disable the T-vis.
As cogs explained, the T-vis effectively increases manifold runner velocity, which in turn improves VE, or more accurately cylinder filling effiency and this in turn improves turbo spool.
Should you disable the T-vis, an efficiently sized turbo will take longer to spool regardless of optimised tuning, as precise tuning of ign & EFI values will improve power by increasing combustion efficiency & raising PCP closer to TDC, but won't effect VE.
Better to leave it operational and enjoy the increased torque and quicker spool it provides when working correctly, stock ECU or standalone.
Should you decide to take manual control of the T-vis as I've done (no choice on a gen3 -:)) you can set an RPM switch point, using an rpm switch that has hysteresis (or ECU2/3), and include a simple boost over-ride circuit, or pressure switch, to open at a selected point according to the spool characterists of the turbo your using. This way the operation of the T-vis becomes predictable and more beneficial, closing off idle and opening prior to VE peaking.
I tuned this arangement basically with the T-vis locked closed up to the switch point, and locked open after, with some enrichment at the switch point itself. This worked out very well, and delivers good power. Recently using 20% bio-flex, it worked out exceptionally well, so might be a good starting point if you want to experiment. Down side is your removing the T-vis operation as an effective safety strategy, but then I'm not convinced its all that effective as such, and more likely used simply because it's there.
Also don't forget USDM ECU's and JDM's are different, the nominal switching point for a USDM is 4400rpm, where as JDM is 3800.