The first time I had a problem was when I was using Methyl Benzene as an octane booster. It disintegrated the short hose inside the fuel tank that is between the pump and the metal pipe. I had to take the tank out to replace it.
At that stage I thought that the hose was just old and didn't know that it was the methyl benzene that had caused it.
I then changed to E85 and I did know about how it disintegrates rubber so I replaced all the fuel lines and modded the car so I could get to the fuel pump without taking the tank out. See photos previously in this thread.
This was all a lot of effort.
As part of the upgrade to E85, I bought new 1000cc injectors and during the engine rebuild, they sat around in the garage and seized completely.
It was at that stage that I said enough is enough. I need the car to be reliable.
If you have a look on Google, you will see lots of stories like this about E85.
It is also absorbs water from the air (makes it go off quickly) and is more corrosive to metals than water.
That's why I've given up on it. I have spent a lot of time and money due to E85 and all I got was a broken car.