It could be a problem, if you were to run say 10%E on the haltec programmed for 98ULP there would only be a marginal change, but say 20% could be different, dependant on the level of tune.
As for programming for the mix you select, you'd have to get some idea of the spread of this seasonal change, and program accordingly. I'm not sure what exactly they are talking about, if it's simply adding a higher % of ULP, that's no real issue, although the RON rating might take a bit of a hit at say 15% of 91 added, relatively speaking.
As far as octane goes, I've been messing around with dual tunes on 650's and apart from being long winded, I've come to realise just how much Ign advance this stuff will tolerate..you actually have to go looking for knock.
I think a chipped ECU like a Blitz Access would work very well on a 20% E mix. In fact I suspect the stock ECU's could handle an additional 2deg initial advance also, without trying it yet.
In fact I'd like to get my hands on a Gen3 Blitz ECU and give it a go. Be a nice little stock replacement power up package with 20%E. (anyone got one f/s? -:)